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At some point in the mid-24th century, Abaddon bought the alien ship from a Haakonian captain. Abaddon tried turning the ship into a towing vessel, but found the ship to require constant repairs. Abaddon found that its neurogenic interface made him see a woman, the personification of the alien ship. She told him that he was incompatible with her systems, and to find a pilot that was. He decided not to tell future prospects about this detail. This ship was programmed with an adaptive program that manipulated the pilot into piloting the ship to a predetermined location.
Lieutenant Tom Paris of the USS Voyager bought the shuttle from Abaddon's Repository of Lost Treasures in 2376. Harry Kim, who Tom Paris had volunteered to help restore the alien ship, assisted him in trying to start the ship up for the first time. Paris decided to name it "Alice", after Alice Battisti, whom he had pursued at the Academy. They found that the ship's power systems burned through power cells quickly, and just starting it up and running the neurogenic interface burned another one out.Paris became obsessed with the alien ship to the point that he started ignoring B'Elanna Torres.Alice was able to project itself in Paris' mind as an attractive woman. The more Tom used the interface, the more he came under control of it. When Paris began to resist Alice and attempted to go to sickbay, Alice was able to send a small shock to Paris' brain, causing severe pain. With this "Alice" was able to make him launch the craft, and Tom became one with the machine and headed for a particle fountain, which Alice referred to as "home". Because Paris' mind was linked with the ship, weapon's fire from Voyager hurt Paris directly. To defeat this Janeway ordered The Doctor to link Paris' and B'Elanna Torres' minds to distract Paris long enough to allow Tuvok to shut Alice down and beam Paris back to Voyager before Alice was destroyed in the particle fountain. (VOY episode: "Alice")
One of Alice's many features was a neurogenic interface, which allowed a pilot to physically bond with the alien ship's computer. When the pilot was seated, a brace would extend from the headrest of the pilot's chair halfway around the pilot's head. This allowed the alien ship to read the pilot's thoughts. (VOY episode: "Alice")