Alpha Varangis was a star system located near the Klingon Neutral Zone.

In 2251, the USS Republic, on a cadet training mission, was to perform a survey of the system, before being diverted to Heir'tzan. (TOS - My Brother's Keeper novel: Republic)

The stellar notation using the Greek language letter "alpha" indicates that there might be a star group or constellation of some sort named "Varangis", of which Alpha Varangis would logically be indicated to be the most prominent star or system.