The Alps were a mountain range in southern Europe on Earth.
In 218 BC, Carthaginian general Hannibal crossed the Alps with an army that included war elephants. (DS9 novel: Antimatter)
In 2267 the Guardian of Forever sent James T. Kirk, Spock and Doctor Leonard McCoy back to the Alps in 218 BC to capture Tengur before he interfered with Hannibal's march. Dr. McCoy recognized the Alps from his previous skiing visit when he was a medical student. (TOS comic: "No Time Like the Past")
In his childhood, Captain Jean-Luc Picard spent much time in the Alps. (TNG novel: The Captains' Honor)