For the regular universe counterpart, see Amanda Grayson.

In the mirror universe, Amanda was the Terran wife of Sarek and mother of Spock. Spock often criticized his father for choosing to mate with a human, although he considered this ironic when he himself chose a human lover, Marlena Moreau, in 2267. That same year, Amanda boarded the ISS Enterprise with her husband, to attend an imperial conference on Babel. Amanda attempted to repair the rift that had developed between her husband and son after Spock joined the Imperial Starfleet. (TOS novel: The Sorrows of Empire)

Amanda's surname of "Grayson" has not been confirmed in the mirror universe.