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Andromeda could refer to:
- Starships and vehicles:
- Andromeda-class (24th century), a class of Federation starship in use in the late 24th century
- USS Andromeda (NCC-2505), a Federation Constellation-class heavy cruiser
- USS Andromeda (Akira-class), a Federation Akira-class heavy cruiser
- USS Andromeda (Galaxy-class), a Federation Galaxy-class explorer
- Andromeda-class (25th century), a class of Federation exploration cruiser in use in the early 25th century
- USS Andromeda (NCC-47700), lead ship of the Andromeda-class