Aneher II was an inhabited planet and the fourth in the Aneher star system. Aneher II was located inside the Federation-Klingon Neutral Zone.

Serenity colony was established by the United Federation of Planets on Aneher II in the 2260s, under the guidance of Daniel Latham. Due to the terms of the Organian Peace Treaty, Klingons also established a colony on the planet. (ST novel: The Case of the Colonist's Corpse)

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