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Arsenic
Arsenic (As) is a chemical element that is classified as a metalloid.
On Earth arsenic was first identified in the year 1250. To humans, the substance was extremely poisonous, and exposure would often lead to a painful death.
For Klingons however, arsenic was not poisonous. In fact arsenic was a necessary part of the Klingon diet, and a arsenic deficiency could lead to a number of health problems for a Klingon. (TOS novel: Doctor's Orders)