Arvada III was the location of a Federation colony.
Beverly Crusher spent a significant portion of her childhood there. In 2339, Beverly encountered a crashed vessel containing diseased refugees from Kevratas, a Romulan subject world. This may have inspired Beverly to pursue a medical career. (TNG novel: Death in Winter)
In his career, Starfleet Intelligence agent Lieutenant Elias Vaughn bore witness to a genocidal holocaust on Arvada III. T'Prynn was also involved in Vaughn's mission to Arvada III. (DS9 novel: Avatar, Book One, TNG novel: The Battle of Betazed, ST - The Lost Era novel: The Art of the Impossible)
- The event witnessed by Vaughn as described in Avatar may well be an alternate take on the Arvada III tragedy to that described in Death in Winter. Alternatively it could be another completely unrelated tragic event on the world. The novel The Art of the Impossible mentions that Vaughn's experience at Arvada III was in 2346.
In the late 26th century, Arvada III was still a Federation planet, and was considered as a place to temporarily house Kelvan refugees from the Andromeda Galaxy. (TOS - Strange New Worlds 9 short story: "Gone Native")