The B'Saari were a sentient alien civilization native to the planet B'Saari II, a homeworld located in the B'Saari star system, somewhere in the galaxy's Alpha or Beta Quadrants.

The B'Saari were the first race that the Denobulans made first contact with. Many Denobulans thought that they were the only intelligent race in the galaxy and refused to believe the evidence before their eyes. (ENT episode: "Future Tense")

The B'Saari had the ability to revive the dead in a similar manner to that in the Earth movie Frankenstein. (ENT episode: "Horizon")

In the year 2157, Romulan Admiral Dagarth deceived a group of B'Saari scientists into providing her with a mutagenic virus that she used against Haakona Prime. (ENT - The Romulan War novel: To Brave the Storm)

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