Bicea was a planet along the Federation-Klingon Neutral Zone. A disputed world, it was given by the Organian Peace Treaty arbitration to the United Federation of Planets, but the Klingon Empire never accepted the judgment and continued the claim. Despite the dispute, it was one of the main Federation port colonies on the border with over 200,000 colonists.

After the Klingon massacre of Lursen Prime, an Andorian family of ambassadors built a new life there and were the primary Andorian ambassadorial presence in that sector. However it was the target of another massacre by unknown forces in the late 23rd century, which left no survivors. The USS Sentinel gave the first reports. Cadet Vanda M'Giia, believed the massacre was staged by Klingons. (TOS novelization: Starfleet Academy)