Bipolar disorder, or manic depression, was a mental condition characterized by alternating periods of extreme moods. In one stage, the individual could be in a mania, in which they were intense happy, excitable, energetic, and focused on completing tasks. However, this was followed by periods of depression.

Drugs could help, but not totally remove the condition.

Manic depression was one of a number of handicaps that randomly afflicted Grey Orions, due to their genetic mutilation. (FASA RPG - The Orions module: Book of Deep Knowledge)

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