Still in command by 2156, Ramirez and the Intrepid took part in a war game with one of Enterprise's shuttlepods. This test allowed Starfleet to determine what was wrong with the warp detection grids installed in many star systems. After the war game, Ramirez had dinner with the other participants in the game, Captains Archer, Hernandez, Narsu, and Shumar.
In an alternate timeline where the Xindi's weapon successfully destroyed Earth, the Intrepid was one of the few Earth Starfleet starships to survive, and go on to protected the colony of survivors on Ceti Alpha V. Ramirez was about to stand down as captain in 2165, to be replaced by Malcolm Reed, when the Intrepid was severely damaged in a Xindi attack. (ENT episode: "Twilight")
- ENT episode & novelization: The Expanse
- ENT novel: Beneath the Raptor's Wing
- ENT novel: To Brave the Storm (mentioned only)