Talleyrand was well known as a talented negotiator. He served with France's royal regime, through the French Revolution, during Napoléon Bonaparte's rule, and even after the Restoration. He was once anointed as a christian bishop, but then excommunicated by the church. He was also known for his frequent affairs with women and even for taking bribes. Despite these problems, with his skills he survived throughout this turbulent and dangerous period of French history.
In 2369, Jean-Luc Picard used Talleyrand as an example to teach diplomacy to Worf, encouraging him to find a solution to the Votar VII dispute that suited Worf's style (TNG comic: "A Matter of Dates").