Christopher Columbus (circa 1451 – May 20, 1506) was a human originally from Genoa, Italy on Earth who lived during the 15th and 16th centuries. An explorer, Columbus led an expedition for the Spanish which led to the Europeans discovering new lands across the Atlantic Ocean.

Captain Benjamin Sisko felt that the Cardassian people held the High Gul of the Crescent Order in the same light as humans held Columbus and George Washington in. (DS9 novel: Station Rage)

Captain Jean-Luc Picard felt like Columbus or Magellan during the USS Enterprise's mission to breach the galactic barrier. (TNG novel: Q-Space)

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