Cluster Telpha-Z is a star cluster in the Milky Way Galaxy. It was charted by the USS Enterprise on Stardate 21:06.7.

It is home to the planet Metamorpha. It is also the site of the Timsonian Institute. (TOS comic: "The Peril of Planet Quick Change", SCE eBook: The Future Begins)

In the original comic book, the location of Metamorpha was referred to as "Galaxy Telpha Z", but this was retconned by The Future Begins to merely be a star cluster.