Columbia could refer to:
- Starships and vehicles:
- Columbia (N4A), a 20th century airship
- Columbia (OV-102), a NASA space shuttle
- Columbia (NX-02), an Earth Starfleet starship
- SS Columbia, a Merchant Marines surveyor
- SS Columbia (mirror)
- USS Columbia (NCC-163), Minuteman-class, aka Minuteman
- USS Columbia (NCC-621), Hermes-class
- USS Columbia (NCC-2002), Excelsior-class
- USS Columbia (Steamrunner class), a 24th century ship
- USS Columbia (NCC-170147), Galaxy X-class
- Other
- Columbia River, a North American river
- Columbia University, the alma mater of Rabbi Rachel Gilman
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