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A coolant is a substance that is used to regulate temperature of another material, gas or liquid through a form of chemical reaction. In the ecology of many planets inhabited by carbon-based lifeforms, water can act as a coolant in many basic situations and life processes. Races and cultures from multiple galaxies that develop industry often use advanced knowledge of chemistry to devise powerful and effective coolants to regulate the temperature of technology for safety and operational reasons. (TOS video game: Star Trek) Complex coolants often involve extreme chemical reactions, and often prove inimical to humanoid life, requiring that they be carefully contained. Volatile coolants are used in the technology of many notable civilizations of the Milky Way Galaxy. (TOS episode & Star Trek 1 novelization: Balance of Terror; TNG movie, novelization & comic adaptation: First Contact) Coolant is commonly referred to by the technology it is applied to, such as phaser coolant or plasma coolant, or as the form in which it is delivered, such as coolant gas.
An unspecified liquid coolant was used by the Gorn who traveled from another galaxy to Federation space in the Kelvin timeline. Disrupting its flow in the Gorn systems was instrumental in aiding James T. Kirk and Spock's incursion on their facility. (TOS video game: Star Trek)