Ensign Duane Wilkens was a Human male serving in Starfleet in the late 24th century.

In 2370, Wilkens served as a security officer on Deep Space 9, he was often partnered with Ian Muckerheide as the two made an effective team. In that year he, Muckerheide, Dalia Parks, Sven Jonsson and Natalia Aponte made up the security contingent on the runabout USS Amazon along with Julian Bashir, Jadzia Dax and Kira Nerys, in a mission to rescue a Horta which had been kidnapped by the Cardassians. (DS9 novel: Devil in the Sky)