Designed and built as a new variant of the famed Constitution-class starships, the Exeter-class honored the 400 crew members of the USS Exeter who were killed by a biological agent in 2268. The Exeter-class starship has specialized equipment that can modify torpedoes to seek the engine emissions of cloaked vessels. This technology was inspired by the modifications made to a torpedo by Spock and Leonard McCoy during the battle against GeneralChang at Khitomer in 2293.
The Exeter-class is listed as a "Federation cruiser refit", and comes equipped with a special console that, when activated, causes the next torpedo fired to seek the ionizedgas emissions of nearby starships. (STOvideo game: Star Trek Online)