The Federation Bureau of Scientific Investigation was a branch of the Department of Scientific Research and Development. It was charged with the evaluation of new scientific breakthroughs as well as inventions for both civilian and military application. As such, it maintained permnant staff members at both Terra's University at Sol III and the Vulcan Science Academy. (FASA RPG module: The Federation)

In 2267, the Vulcan Science Academy reported to the Bureau of Scientific Investigation of psionic contact being made with the Tholian race. However, this report was filed away and promptly forgotten. (FASA RPG module: Star Trek IV Sourcebook Update)