The Federation Subcommittee on Internal Interstellar Affairs is a fact-finding committee of the Federation Council charged with issues regarding internal Federation politics.

In 2286, the head of this committee was Thrandasar v'Elex of Andoria. Her speech to the Federation Council that year identified the largest threat to Federation stability as ambitious individuals and corporations flagrantly disregarding planetary sovereignty and the Prime Directive. She called for tougher enforcement of the Prime Directive, including an increased Starfleet presence. (FASA RPG module: Star Trek IV Sourcebook Update.)