The Ferengi/Hupyrian Friendship Brigade was a military alliance formed between the Ferengi Alliance, under the leadership of Grand Nagus Oblat, and a faction of Hupyrians opposing the Hupyrian People's Unity Front in the Hupyrian Conflict.

All Ferengi personnel in the Ferengi/Hupyrian Friendship Brigade were given a can of Hupyrian beetle snuff each week. The popularity of the snuff was credited with increasing enrollment enough to allow the Brigade to be victorious in the Conflict. (DS9 reference: Legends of the Ferengi)