First contact could refer to:

• First contact, the first contact between species
• First Contact Day, a day celebrating the first human-alien contact
• First Contact Office, an office in Starfleet dedicated to first contact
• Real world items:
  • First Contact (episode), a TNG episode
  • Star Trek: First Contact, the eighth Star Trek movie
  • First Contact (CCG), a CCG set
  • First Contact Day (STO), an STO mission