In the alternate reality which the Time Lord known as the Doctor called home, fixed points in time were immovable events that could not be altered. The Doctor identified the Battle of Wolf 359 as a fixed point in time, warning his human companions against preventing the tragedy. (TNG - Assimilation² comic: "Issue 7")
Kathryn Janeway's death across the multiverse around stardate 57445 (2380) was a fixed point in time, according to Q. (VOY novels: The Eternal Tide, Acts of Contrition)
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