Fred or Frederick could refer to:
- People
- Fred (Enteroli), owner of a bar on Enterol VI's orbital refueling station
- Fred (Glaeziver), a Glaeziver crewmember aboard the USS Grissom
- Fred Astaire, a 20th century dancer, singer, and actor
- Fred DiMuro, a USS Reliant crewmember
- Fred Haise, CO of Earth's space shuttle Enterprise
- Fred Haskem, the governor of Menith-II
- Fred MacDougan, President Nanietta Bacco's communications director
- Frederick McLaren, one of the foremost experts in zero gravity operations
- Fred Noonan, Amelia Earhart's navigator
- Fred Smith, an engineer
- Fred Withers, the uncle of Joanna McCoy
- Frederick II of Prussia, a.k.a. Frederick The Great, a Prussian King
- Frederick Douglass, a 19th century American statesman and writer
- Frederick de Winter, a farmer on Sheridan's World
- Frederick Kimbal, Wesley Crusher's roommate at Starfleet Academy
- Frederick La Rouque, a 19th century professional gambler
- Frederick William Jefferies, inventor of Jefferies tubes aboard Federation starships
- Frederico, the cousin of Vicenzo Farrenga
- Real-world topics
- Fred Goldstein, co-author of the Spaceflight Chronology
- Fred Pienkos, a digital artist
- Frederick Kim, a Strange New Worlds contest winner
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