The Gamma 7A system was a star system located in sector 39J of the Milky Way Galaxy.

In 2268, the USS Intrepid was surveying the Gamma 7A system, during which time, the system and ship were destroyed by a giant space amoeba, and the systems' billions of inhabitants were killed. This amoeba was later stopped by the crew of the USS Enterprise. (TOS episode: "The Immunity Syndrome")

In 2259 of the alternate reality created by the Narada's temporal incursion, the USS Enterprise participated in a mission to the system. Said mission earned Nyota Uhura a Special Commendation. (Star Trek App)

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