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The virus was transmitted via injection. A Gorn drone would approach the victims from the front, grab them from behind with extendable arms, and panels would open up to reveal a large bore needle that was inserted into the victim's spinal column.
Symptoms of the virus included oozing fluid similar in appearance to Gorn blood (perhaps the unknown toxins McCoy identified early on), as well as a compulsion to seek and attack friendlies such as Kirk and Spock. Weapons used included firearms, metallic rods (unnamed weapons), and, in Spock's case, fists.
The victims, while unable to control their actions, seemed to realize that they were doing something wrong, as they would frequently call out to alert others to watch out for them.
The antidote for this virus was synthesized by McCoy, who instructed Kirk and Spock to release it in the atmospheric generators. This ensured ship-wide dispersal. The antidote was successful in curing the virus. However, the Gorn didn't seem to care for it, according to Scotty.
Victims of this virus included Vulcans on Helios-1 and New Vulcan, personnel on Starbase Frontier 17, crew members of the Enterprise, and Spock. Under its influence, Spock got into a fistfight with Kirk, who kept him at bay long enough to allow Sulu to pilot the shuttle into the arena. There, while leaning out of the open back door, McCoy shot Spock with a dart rifle loaded with the antidote. Spock's recovery was almost instantaneous. (TOS video game: Star Trek)