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Guthrie was a female yeoman in Starfleet in the 23rd century. In 2263, she was assigned to Commodore Matthew Decker of the USS Constellation, replacing Yeoman Lawford. (VAN novel: Harbinger, TOS - The Brave and the Bold, Book One novella: The First Artifact)
- Guthrie presumably perished with the rest of the Constellation crew in 2267 during the encounter with an ancient "planet killer" depicted in TOS episode: "The Doomsday Machine".