The Hotel Palaestro was a hotel operating in the city of Rome, Italy, in the late 20th century. In 1974, the International Conference on Genetic Research and Experimentation was held in the hotel. Roberta Lincoln, using the cover identity of Dr. Veronica Neary, stayed at Room 11-G of the Hotel Palaestro while infiltrating the conference. (TOS novel: The Rise and Fall of Khan Noonien Singh, Volume 1)

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