Ishka was the wife of Keldar, the mother of Quark and Rom and the paternal grandmother of Nog and Bena. Ishka was not a typical Ferengi female and felt that the attitude of her people to women was wrong. Ishka was a shrewd business person, even better than her husband, and, by the 2370s, had earned quite a lot of money. Ishka became an important figure in the Ferengi Alliance when Grand Nagus Zek began to support her calls for equal rights for Ferengi females.
The Ferengi Commerce Authority became aware of her profit-earning in late 2371 and Quark was ordered to get her to sign a confession and to give it all away. Quark and Rom managed to get her to confess, but Ishka was able to hide away two thirds of her total fortune. (DS9 episode: "Family Business")
While Ishka was attending a tongo championship, she helped the struggling Grand Nagus Zek to win. The two later became romantically involved. Brunt and Quark later found out Ishka was now helping Zek to run the Ferengi Alliance. (DS9 episode: "Ferengi Love Songs")
In mid-2374, while on her way to Vulcan, Ishka was captured by the Dominion. Later, her sons Quark and Rom were able to rescue her by arranging an exchange with Yelgrun in which Keevan was handed to the Dominion in place of Ishka. (DS9 episode: "The Magnificent Ferengi")
Later in the year, Ishka fled Ferenginar with Grand Nagus Zek after the reforms allowing females to appear in public were introduced but caused panic and disruption, leading to Zek being deposed as Grand Nagus. Ishka was to meet with Nilva of Slug-o-Cola and seek his influence to restore Zek's position, but suffered a heart attack before she could do us. Quark agreed to pose as "Lumba", a female Ferengi and Nilva agreed to help Zek. (DS9 episode: "Profit and Lace")
In 2375, Iskha journeyed with Zek to Deep Space 9, where Zek named Rom as his successor as Grand Nagus, with the assumption that Rom would continued Zek's reforms. Ishka and Zek then retired to Risa. (DS9 episode: "The Dogs of War")
- ST - Terok Nor novel: Dawn of the Eagles
- DS9 episode: "Family Business"
- DS9 episode: "Ferengi Love Songs"
- DS9 episode: "The Magnificent Ferengi"
- DS9 episode: "Profit and Lace"
- DS9 episode: "The Dogs of War"
- TNG - Gateways novel: Doors Into Chaos
- DS9 - Worlds of Star Trek: Deep Space Nine novel: Ferenginar: Satisfaction is Not Guaranteed