The Kar-telos system is a star system in the Gamma Quadrant which is located within ten light years of the terminus of the Bajoran wormhole.
In 2372, the USS Defiant performed maneuvers through the asteroid belt in the Kar-telos system. (DS9 episode: "Bar Association")
In 2376, the Halloran was transported to the Kar-telos system by an Iconian Gateway. The USS Sungari was sent to escort them to Deep Space 9. (DS9 - Gateways novel: Demons of Air and Darkness)
Later in 2376, the crew of the USS da Vinci pursued the Wadi Tellow to Kar-telos. (SCE eBook: Malefictorum)