The Kepla sector is a sector in the Alpha Quadrant.

In 2373, on the first day of the Dominion War, the Dominion swept into the Kepla system. The USS Valiant was in the sector at the time and was trapped behind enemy lines due to the Dominion advance. (DS9 episode: "Valiant")

During the Starfleet retreat from the Kepla system, Lieutenant Guy Marlow was shot in the chest. (DS9 novel: Hollow Men)

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