Khitomer was the name of a trinary star system located in Klingon Empire space, the location of planet Khitomer, the home of a Klingon colony and outpost that was destroyed by Romulan attack in the 2340s. (TNG episode: "Sins of the Father")

In a reality where the galaxy's races and cultures collapsed into full-scale war in 2364, Khitomer was one of the systems embroiled in the breakdown of diplomacy. Khitomer produced only about a quarter of the resources as the Klingon system, and fell out of Klingon control around the time of that conflict, occupied by a Borg fleet. (ST video game: Conquest)