Kirk could refer to:
- James T. Kirk, captain of the USS Enterprise (NCC-1701) and USS Enterprise-A.
- James T. Kirk (alternate reality), captain of an alternate USS Enterprise, with a different past and destiny.
- James T. Kirk (mirror), the primary universe Kirk's mirror universe counterpart.
- James T. Kirk (mirror) (alternate reality) from an alternate version of the mirror universe.
- Jane Kirk, a parallel universe incarnation.
- Jane T. Kirk, a female incarnation of Jim Kirk apparently from a parallel universe.
- Jane Tiberia Kirk, a female incarnation of Jim Kirk from an alternate reality.
- James (duplicate), a duplicate of James T. Kirk created through the Phoenix Process.
- James T. Kirk (android), two android duplicates created on Exo III.
- Kirk Defense, a tactic used by James T. Kirk.
- Kirk family:
- Samuel Abraham Kirk, great-grandfather of James T. Kirk.
- Tiberius "Samuel" Kirk, son of Samuel and grandfather of James T. Kirk.
- James Kirk, son of Samuel.
- George Samuel Kirk, Sr., son of Samuel and father of James T.
- George Samuel Kirk, Sr. (mirror), mirror universe counterpart.
- Benjamin Kirk, another man considered to be James T. Kirk's father.
- Eugene Claudius Kirk, an alternate James T. Kirk father.
- Winona Kirk, wife of George.
- Winona Kirk (mirror), mirror universe counterpart.
- George Samuel Kirk, Jr., son of George and Winona.
- George Samuel Kirk, Jr. (mirror), mirror universe counterpart.
- Aurelan Kirk, wife of George Jr.
- Peter Kirk, son of George Jr.
- Alexander Kirk, son of George Jr.
- Julius Kirk, son of George Jr.
- Craig Kirk, son of George Jr.
- Sinjin Kirk, son of Craig.
- Jamie Samantha Kirk, 24th century Kirk.
- Joseph Kirk, the son of James T.
- Abernathy Kirk, an ancient relative of James T.
- Starships and vehicles:
- ISS Kirk
- USS James T. Kirk (Akira-class), a Starfleet Akira-class heavy cruiser active in the late 24th century
- USS Kirk (NCC-91277), a Starfleet Exeter-class cruiser active in the early 25th century
- Shuttle Kirk
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