Largo V was a planet located somewhere in the space of the galaxy's Alpha or Beta Quadrants, the fifth planet in orbit of the Largo star system.

Horace T. Mudd ran a tribble torture farm on Largo V at some point prior to the year 2371. (DS9 comic: "Mudd's Pets, Part I")

In 2369, Jaheel was to deliver a shipment of Tamen sahsheer to Largo V. (DS9 episode: "Babel")

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