Lejico was one of three major cities on the surface of Ardana in the mid 24th century, behind First City and Droxana. (CoE eBook: Signs from Heaven)

A major earthquake struck Lejico in 2381. Among those killed were four Starfleet crewmembers from the USS Sugihara: Crewman Jomat, Crewman Linnea Palmer, Ensign Letitia Shawan, and Chief Rupi Yee. (ST novel: A Singular Destiny)