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Levodian flu was an illness harmless to most humanoids. Its symptoms included fever, chills, and the sniffles.

In 2154, Antaak's attempts to create Klingon augments resulted in a mutated form of the Levodian flu virus. (ENT episode: "Affliction")

The Levodian flu virus was easily adapted as a way to spread bioengineered plagues. By the mid 23rd century it had been in use within the Klingon Empire for biological projects for over one hundred years. A Trill colony was once infected by the Levoidan flu virus, causing them to develop facial ridges and lose the spotting that the vast majority of Trill possessed. (TLE novel: Excelsior: Forged in Fire)

Information about this type of flu could be found in the USS Voyager's computers by 2376. (VOY video game: Elite Force)

In 2409, the chief medical officer of Listening Post Hephaestus, Lieutenant Livok, reported two cases of Levodian flu. (STO mission: "Mine Enemy")

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