- Lecrotox
- Lecroutex
- Lectrazine
- Ledahn Muri
- Ledbetter
- Ledonia III
- Ledonia Prime Shipyard
- Ledonne
- Ledos
- Ledos-Ventu system
- Ledoy
- Lee
- Lee (24th century)
- Lee (Aleph Prime)
- Lee (USS Copernicus)
- Lee Block
- Lee Contini
- Lee Contini (23rd century)
- Lee Contini (24th century)
- Lee Correy
- Lee Faust
- Lee Kelso
- Lee Kelso (Kelvin timeline)
- Lee Kuan
- Lee Kuan (mirror)
- Lee Majors
- Lee Sterling
- Lee Stringer
- Lee Wayne
- Leeding Engines Limited
- Leej Terrell
- Leejay
- Leen
- Leesha
- Leet
- Leeta
- Leeta (mirror)
- Leevka
- Lefebre
- Lefebvre Peter
- Leff
- Lefler's Logs
- Left Ear
- Lefv
- Legacies
- Legacy
- Legacy (STO)
- Legacy (comic)
- Legacy (episode)
- Legacy (game)
- Legacy (novel)
- Legacy chest
- Legacy class
- Legacy of Romulus
- Legacy of Spock
- Legacy of Spock, Part 1
- Legacy of Spock, Part 2
- Legacy of Spock, Part 3
- Legacy of Spock, Part 4
- Legal Action
- Legan Duravit
- Legan Fin
- Legara
- Legara IV
- Legaran
- Legarn
- Legarratlinya
- Legate
- Legate Damar
- Legate class
- Legate of the Tal Diann
- Legation commander
- Legato infection
- Legendary Kelvin Timeline Intel Battlecruiser
- Legendary Miracle Worker Light Cruiser
- Legendary Pilot Warship
- Legendary Temporal Flight-Deck Carrier
- Legendary Temporal Operative Escort
- Legendary dreadnought cruiser
- Legendary light intel warbird
- Legendary pilot warship
- Legendary starship
- Legends
- Legends of the Ferengi
- Legends of the Iconian Diaspora
- Legion class
- Legion of Assassins
- Legion of Merit
- Legion of Super-Heroes
- Legionary (Augment)
- Legionnaire
- Legionnaire (disambiguation)
- Legira
- Legira II
- Legislative Council
- Legislature of the Vostigye Union
- Lehe'jhme
- Lehman
- Leiber-Kurtzberg Theory
- Leid
- Leif Ericson
- Leif Ericson (disambiguation)
- Leif Ericson (starship)
- Leigh
- Leighton
- Leighton (disambiguation)
- Leijten
- Leikeze Naes
- Leikeze Naes (23rd century)
- Leikeze Naes (24th century)
- Leila Birani
- Leila Kalomi
- Leila Koryev
- Leinarrh
- Leiris
- Leirt
- Lejeune
- Lejico
- Lejonis
- Lejuris
- Lek
- Lekev
- Lekk
- Lekray
- Lekray I
- Lekray II
- Lekray III
- Lekythos
- Lela Dax
- Leland
- Leland Bell
- Leland Lynch
- Lelys
- Lem'sa
- Lem-Tzenketh
- Lem Faal
- Lemanr Tacketo
- Lembatta Cluster
- Lembatta Prime
- Lemdock
- Lemec
- Lemieux
- Lemli
- Lemma II
- Lemnorian
- Lemon
- Lemon chicken
- Lemon pie
- Lemonade
- Lempo
- Lemto
- Lemuel Gulliver
- Len (disambiguation)
- Len Levine
- Len Tanaka
- Len Wein
- Lena Glau
- Lena Goldblum
- Lena Horne
- Lena Shonsui
- Lenandro
- Lenara Kahn
- Lenaris Holem
- Lenaris Holem (mirror)
- Lenaris Jau
- Lenaris Pendan
- Lendal
- Lendrin
- Lenest
- Leng
- Lengtorz
- Lenin class
- Leningorá
- Leningrad (disambiguation)
- Lenith Agreho
- Lenk
- Lenkit Casten
- Lennardi Marcus
- Lennis Delah
- Lennli
- Lenora
- Lenora (disambiguation)
- Lenore Karidian
- Lenox High School
- Lenske
- Lenth Sea
- Lenthal class
- Lentrex
- Lentrex VII
- Leo
- Leo (disambiguation)
- Leo Antonidas
- Leo Brownell
- Leo Lubitsch
- Leo Minor constellation
- Leo Tolstoy
- Leo constellation
- Leola root
- Leola root stew
- Leon Ruszkowski
- Leon Sawchuk
- Leon Trotsky
- Leonard A. Emery
- Leonard James Akaar
- Leonard Llewellyn
- Leonard McCoy
- Leonard McCoy, Frontier Doctor
- Leonard McCoy, Frontier Doctor, Issue 4
- Leonard McCoy (Kelvin timeline)
- Leonard McCoy (alternates)
- Leonard McCoy (mirror)
- Leonard McCoy (mirror Kelvin timeline)
- Leonard Nimoy
- Leonard O'Grady
- Leonard Scott
- Leonardo (NCC-1701/7) (I)
- Leonardo (NCC-1701/7) (II)
- Leonardo Fibonacci
- Leonardo da Vinci
- Leonardo da Vinci (hologram)
- Leonid Brezhnev
- Leonov
- Leopold Seppel
- Leora IV
- Leporazine
- Lept
- Lepton
- Lepus constellation
- Ler'at
- Lerak Kepac
- Leran Manev
- Lerik
- Lerishi
- Lerithan Textiles
- Lern
- Lerner
- Leroan
- Leroth Islands
- Lerow
- Lerow homeworld
- Lerow rocket
- Lerrit
- Lerrit Army
- Lerrit Navy
- Lersom
- Lerxst
- Les (disambiguation)
- Les Buenamigo
- Les Landau (Admiral)
- Les Loups Ne Se Mangent Pas Entre Eux
- Les Misérables
- Les Misérables (mirror)
- Lesira
- Leskanic
- Leskanich
- Leskit
- Lesley Wodehouse
- Leslie (disambiguation)
- Leslie Banks
- Leslie Braeden
- Leslie Collins
- Leslie Lannon
- Leslie Lebrun
- Leslie Thompson
- Leslie Thorne
- Leslie Wong
- Lessa (disambiguation)
- Lessenar
- Lesser Andorian
- Lesser Evil
- Lessons
- Lester
- Lester (disambiguation)
- Lester Foster
- Lester Johnson
- Lester Levesconte
- Lestewka
- Lesurgis
- Lesurgis XXXII
- Let's Find Out About Andorians
- Let's Get Away from It All
- Let He Who Is Without Sin...
- Let Sleeping Borg Lie
- Let That Be Your Last Battlefield
- Letan
- Letant
- Letau
- Letau prison facility
- Letek
- Letek (Ferengi)
- Leterik
- Letharna
- Lethe
- Lethe (disambiguation)
- Lethe (episode)
- Lethean
- Lethean veteran asylum
- Lethik
- Lethozine
- Lethra Hanno
- Letix Kortaj
- Letters of Marque
- Letters to Captain Proton
- Letting Go
- Leughon
- Leughon sector
- Leung
- Lev
- Levaeri V
- Levak
- Levarr Jordan
- Levass
- Levesconte
- Levi's
- Levi Ben Zoma
- Leviathan
- Leviathan, Part Two
- Leviathan (comic)
- Leviathan (disambiguation)
- Levine
- Levinius
- Levinius V
- Levintine Expanse
- Levitasz
- Levithi nut
- Levitz
- Levodian flu
- Levok
- Levy
- Lewa
- Lewis
- Lewis (Starbase 27)
- Lewis (USS Enterprise)
- Lewis (shuttlecraft)
- Lewis (subengineer)
- Lewis Baker
- Lewis Carroll
- Lewis Chang
- Lewis Colony
- Lewis Elementary School
- Lewis Nevin
- Lewis Rosenhaus
- Lewis Zimmerman
- Lewis Zimmerman (mirror)
- Lewis and Clark Corps of Discovery Cross