The M'klexa were a humanoid civilization native to a world the space of the galaxy's Alpha or Beta Quadrants. They had bulbous heads, at least four eyes that were five times the size of those of a Vulcan, and four upper limbs. (ENT - The Romulan War novel: To Brave the Storm)

They were encountered by the Valakians sometime prior to the 2150s. (ENT episode: "Dear Doctor")

The M'klexa and Vulcans had first contact only a short time before the year 2156, but relations between the two species was peaceful.

In 2156, the Enterprise encountered a disabled M'klexa ship and got them under way successfully. (ENT - The Romulan War novel: To Brave the Storm)

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