Mary Klesaris was a female Human physician in Starfleet in the mid 24th century. As of 2369, she held the rank of Lieutenant, and served on the medical staff aboard the USS Progress, under chief medical officer Katherine Pulaski. That year, she led the trauma units during rescue operation on Drema IV following a dilithium mine collapse.

By 2377, Klesaris was CMO on Drema Station in the Selcundi Drema sector. (SCE eBook: Progress)