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In the 2260s, he served aboard the ISS Enterprise. In 2267, DeSalle became the ship's chief engineer as his predecessor Montgomery Scott was promoted to first officer following Spock's assassination of Captain James T. Kirk. Scott was never very happy as executive officer, feeling that he left engineering in less capable hands, often times supervising work in engineering from the bridge.
|ISS Enterprise (NCC-1701) personnel|
|Robert April • Phillip Boyce • Christine Chapel • Pavel Chekov • J. Mia Colt • Robert D'Amato • Willard Decker • Michael DeSalle • Fein • Finney • Karl Franz • Gaffney • David Garrovick • Hadley • Idelson • Ilia • James T. Kirk • Winston Kyle • Roger Lemli • Jabilo M'Benga • Leonard McCoy • Marla McGivers • Marlena Moreau • Number One • Carolyn Palamas • Elizabeth Palmer • Christopher Pike • Janice Rand • Kevin Riley • Saavik • Montgomery Scott • Elizabeth Sherwood • Solok • Spock • Stang • Hikaru Sulu • Nyota Uhura • Xon • unnamed ISS Enterprise personnel|
|Chief engineers of the starships Enterprise|
|Enterprise (NX-01)||Tucker • Kelby • Burch|
|USS Enterprise (NCC-1701)||Kursley • Marvick • Powell • Fourrier • Pitcairn • Barry • Grace • Burnstein • Scott|
|USS Enterprise (NCC-1701) (alternate reality)||Olson • Scott|
|USS Enterprise (NCC-1701) (other alternate realities)||Scott|
|USS Enterprise (NCC-1701-A)||Scott|
| USS Enterprise (NCC-1701-A)|
|USS Enterprise (NCC-1701-B)||Buonarroti • Jennings|
|USS Enterprise (NCC-1701-C)||Kodell|
|USS Enterprise (NCC-1701-D)||MacDougal • Argyle • Logan • Lynch • La Forge|
|USS Enterprise (NCC-1701-D) (alternate realities)||Argyle • Crusher|
|USS Enterprise (NCC-1701-E)||La Forge|
|USS Enterprise (NCC-1701-E) (alternate realities)||Argyle • Crusher|
|ISS Enterprise (NX-01)||Tucker|
|ISS Enterprise (NCC-1701)||Scott • DeSalle|
|ISS Enterprise (NCC-1701-D)||La Forge|
|ISS Enterprise (NCC-1701-E)||O'Brien|
|Free Starship Enterprise||Barclay|