The Moon Zephyr was a civilian transport in service in the 2370s. It possessed no armaments of any kind.

In 2374, during the war, the Moon Zephyr was attacked by the Jem'Hadar near the Federation-Cardassian border. Among those killed were Setheleyis th'Rasdeth, Tihana Elkhur and Shavnah Hakim. The bodies of those killed were brought to Deep Space 9 for identification. (DS9 short story: "The Devil You Know")