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In 2372, while on Earth helping Starfleet to find ways to detect Changelings, Odo was infected with the disease by Section 31, who hoped he would link with other members of his race and infect them all. (DS9 episode: "When It Rains...")
In 2374, Tomas Roeder discovered the existence of the virus. He attempted to smuggle classified data on Changeling morphology, the damage the virus was doing to it and the names of the designers and others involved to the Dominion. (DS9 novel: Hollow Men)
The Founders began suffering from the effects of the disease in 2375, with the entire Great Link being infected. The Female Changeling was also infected with the disease and her symptoms were noticed by Weyoun and Corat Damar. The Female Changeling informed Weyoun of the disease and the fifth clone of Weyoun informed Odo of it when he attempted to defect to the Federation. (DS9 episode: "Treachery, Faith, and the Great River")
The Vorta began research into a cure for the disease, but had no success. The Female Changeling had them document their findings before ordering Weyoun to execute them and activate their clones, hoping for a "fresh perspective". (DS9 episode: "Penumbra")
Late in 2375, Julian Bashir discovered Odo had become infected with the disease and began research into a cure. Despite his efforts, Bashir made little headway and he and Miles O'Brien sent a message to Starfleet Medical that stated that Bashir had found a cure. It was hoped Sloan or another 31 agent would come to Deep Space 9 to confirm it, giving Bashir and O'Brien an opportunity to find a cure from the agent or give them the name of someone who would have it. (DS9 episodes: "When It Rains...", "Tacking Into the Wind")
Towards the end of the war, after successfully luring Luther Sloan to Deep Space 9, Bashir and O'Brien used a multitronic device to link their minds to Sloan's. They managed to find the cure before Sloan died after having committed suicide. (DS9 episode: "Extreme Measures")
The Federation Council debated giving the Founders the cure, although they decided against it, as they felt it could strengthen the Dominion's hand and allow them to win the war. (DS9 episode: "The Dogs of War")
The Female Changeling had become terminally ill with the disease and had been unable to regenerate. Following the Battle of Cardassia, Odo linked with the Founder and cured her of the disease. In return for having the Female Changeling order her forces to stand down, Odo agreed to return home and cure the Great Link as well. Odo returned to the Gamma Quadrant several days later and cured the Link. (DS9 episode: "What You Leave Behind")
The Female Changeling learned that the virus had been created by Section 31, probably during her link with Odo. Odo himself was concerned how the Great Link would react to the information when he returned home. (DS9 short story: "Requital")