Murphy could refer to:
- People:
- Murphy (Starbase 8), a Starfleet officer on Starbase 8
- Murphy (USS Enterprise), a Starfleet officer on the USS Enterprise
- Murphy (science), a Starfleet officer on the USS Voyager
- Carl Murphy, an embassy employee
- Colin Murphy, a Starfleet officer on the Singularity One project
- Roy Murphy, a Starfleet officer on the USS Enterprise-D
- Telsia Murphy, a Maquis on the USS Voyager
- Murphy (security), a Starfleet officer on the USS Voyager also known as Andreas Colter
- Murphy Wiltz, a Starfleet officer on Starbase 375
- Other
- Murphy's Law, a human aphorism
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