Mutara Nebula

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The Mutara Nebula is an interstellar dust cloud located in the Mutara sector. The nebula contains high levels of static discharge and comprises largely of ionized gases. The combined effect of this makes a starship's sensors highly unreliable and shields inoperable when inside.

In 2285, it was the site of the horrific Battle of the Mutara Nebula. The battle ended when Khan Noonien Singh detonated the experimental Genesis Device inside the nebula, causing matter within it to re-form into the Genesis Planet. TOS movie: Star Trek II: The Wrath of Khan)

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Mutara Nebula article at Memory Alpha, the wiki for canon Star Trek.