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NGC 5078 is a galaxy that is visible form Earth in the Hydra constellation.

During the Borg Invasion of 2381, the USS Aventine and USS Enterprise-E investigated a series of subspace tunnels centralized in the Azure Nebula. One of the tunnels exited the Aventine into the intergalactic void nine hundred eighty-two thousand light years from NGC 5078. (ST - Destiny novel: Mere Mortals)

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