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Neopentothal was a hypnotic drug used in the Federation. In 2274, Dr. Leonard McCoy used neopentothal to place James T. Kirk in a hypnoscan in an attempt to break the memory block he acquired on Helva. (TOS novel: The Prometheus Design)

Neopentothal was first used in the 1956 novel Time for the Stars by Robert A. Heinlein.

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