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Ostenex-E is a medication used to slow the process of loss of bone density.
In 2376, learning that Elias Vaughn's medication of Ostenex-D was having little effect in slowing his loss of bone density, Girani Semna changed his medication to Ostenex-E. (DS9 - Worlds of Star Trek: Deep Space Nine novel: Bajor: Fragments and Omens)