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Outpost T-22 was a Federation facility established on planet Kalandra Minor in late 22nd century. Outpost T-22 was intended as a jumping-off point for colonization efforts; however, most of the planets beyond Kalandra Minor proved unsuitable for colonization, and the outpost was abandoned in the 2260s.
In 2362, with the continuing encroachment of the Cardassian Union, Starfleet decided to make T-22 an active base again. An away team from the USS Aldrin determined the outpost's equipment was obsolete, just before it suffered significant damage in an attack by Romulan smugglers. (NF short story: "Revelations")