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A prefix code was a six digit number programmed into a Starfleet starship's computer that allows someone to take control of a specific starship. These codes are intended as anti-hijacking measures, but have been used for negative purposes. (TNG novel: The Captains' Honor, TOS movie: Star Trek II: The Wrath of Khan)
In 2285, the crew of the USS Enterprise accesed the prefix code of the USS Reliant in order to stop Khan Noonien Singh from using the Reliant against Enterprise. (TOS movie: Star Trek II: The Wrath of Khan)